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Somatic mutations in chromatin remodeler genes could modify the epigenomic landscape of CLL, but They are really unheard of With this malignancy when compared with other lymphoid neoplasms. CHD2 is mutated in 5% of CLL and seven% of MBL.75 The histone methyltransferase SETD2 and ARID1A may also be mutated in a small proportion of sufferers. Of Obse